Famotidine

£16.50

Famotidine 20 mg tablets are prescription-only H₂ receptor blockers that reduce stomach acid to treat reflux, ulcers, and heartburn. Provides long-lasting relief with rapid onset.

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Description

Famotidine 20 mg tablets are a prescription-only treatment for managing excess stomach acid. Commonly used to treat conditions such as gastro-oesophageal reflux disease (GORD), peptic ulcers, reflux oesophagitis, and Zollinger–Ellison syndrome, these tablets offer effective relief from symptoms like heartburn, indigestion, regurgitation, and epigastric pain.

How It Works

Famotidine is an H₂ receptor antagonist that selectively blocks histamine receptors on the stomach’s acid-producing parietal cells. By doing so, it reduces both basal and stimulated gastric acid secretion, helping to soothe irritated oesophageal and stomach linings and promoting healing of acid-related lesions.

Why Choose Famotidine

Compared to fast-acting antacids, Famotidine offers sustained relief that lasts 10–12 hours. It provides a dependable alternative to proton pump inhibitors (PPIs), with fewer concerns about long-term nutrient absorption or kidney impacts. Famotidine has minimal interactions with CYP enzymes, reducing the likelihood of drug interactions. With its quick onset and extended duration, it supports twice-daily or once-daily dosing depending on symptoms.

Important Note

Use Famotidine on a short- to medium-term basis (typically up to 8 weeks). Seek medical advice if symptoms persist beyond two weeks, worsen, or are accompanied by weight loss, difficulty swallowing, or bleeding. Long-term use may require monitoring for potential kidney function changes, magnesium or vitamin B12 deficiency, and risks of intestinal infections. Lifestyle measures like weight management, diet modification, reducing alcohol, stopping smoking, and elevating the head of the bed can improve outcomes and may reduce the needed dose.
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Packaging and branding may vary depending on supplier.

Directions

Always read and follow the patient information leaflet (PIL) provided with the medicine before use.

  • Adults: Take 20 mg twice daily (morning and evening) or 40 mg once daily at bedtime as prescribed.

  • Swallow each tablet whole with water; can be taken with or without food.

  • If a dose is missed and symptoms persist, take as soon as remembered; do not double up.

  • Avoid lying down immediately after taking.

  • Store below 25 °C in original packaging; protect from moisture and light, keep out of children’s reach.

  • Dispose of waste via pharmacy return programs.

Ingredients

  • Active Ingredient: Famotidine 20 mg per tablet

  • Inactive Ingredients: Lactose monohydrate, magnesium stearate, povidone, colloidal silica (check packaging for complete list)

Side Effects

Common Side Effects:

  • Headache

  • Dizziness

  • Constipation or diarrhoea

Serious Side Effects:

  • Irregular heart rhythms (especially with kidney issues)

  • Signs of infection (fever, sore throat)

  • Allergic reactions (rash, swelling, difficulty breathing)

If you notice any symptoms, contact your GP or healthcare professional.

Warnings

  • Contraindications: Allergy to famotidine or other H₂ blockers

  • Cautions: Renal impairment, elderly, liver disease, active GI bleeding

  • Pregnancy/Breastfeeding: Only use when prescribed and under medical supervision

  • Drug Interactions: Caution with atazanavir, itraconazole, ketoconazole, digoxin, and other pH-dependent drugs

  • You may start feeling relief within 1 to 3 hours of taking a dose. For some conditions, it can take a few days of regular use to feel the full effect.
  • Yes, you can take them with or without food. If you’re using it for heartburn, taking a dose before eating can help prevent symptoms.
  • Yes, it’s often prescribed for daily use to manage ongoing acid-related conditions. Always follow your doctor’s advice on how long to take it.
  • Yes, but it’s best to space them out. Take Famotidine at least 1–2 hours before or after using antacids, unless your doctor advises otherwise.
  • You should speak to your doctor or midwife before taking Famotidine if you’re pregnant or breastfeeding, to make sure it’s suitable for you.